Células Granulares Eosinofílicas/Células Mast (CGE/MC) y su relación con los efectos de herbicidas: Caso del Glifosato y surfactantes acompañantes en peces

Eosinophlic granular cells/Mast cells and their relation with the effects of herbicides: Case of glyphosate and accompaning surfactants on fish

Contenido principal del artículo

Jeraldyn Argüello-Rangel
Pedro A. Triana-García
Pedro R. Eslava-Mocha

Resumen

Los Mastocitos, Células Granulares Eosinofílicas (CGE) o células Mast de los peces (MC) pertenecientes al sistema inmune, han sido relacionadas en diferentes tipos de respuestas fisiológicas y patológicas en peces. Recientemente, se ha incrementado el interés científico relacionado con su participación en reacciones ante contaminantes acuáticos, así mismo, frente a agentes infecciosos y últimamente como modelos de peces para estudiar enfermedades que involucran desordenes alérgicos y alteraciones neurodegenerativas en los seres humanos. Numerosos trabajos en varias especies de teleósteos han demostrado que los comportamientos de CGE/MC son relevantes para estudiar mecanismos anti-infecciosos. Así mismo, se ha estudiado su respuesta ante la exposición a contaminantes tales como los herbicidas, que pueden interferir con el sistema nervioso y el olfato de los peces. Se muestran datos de trabajos sobre mastocitos de peces y se sugiere la importancia de estudiarlas también como biomarcador ante contaminantes. En esta revisión se enfatiza su participación en las respuestas de diferentes órganos y tejidos ante la exposición a herbicidas como el glifosato y los surfactantes acompañantes en las mezclas asperjadas, su morfología, su papel fisiológico y patológico, y sobre algunas posibles formas de estudiarlas en el sistema nervioso, especialmente, frente a exposiciones subletales a pesticidas.

Palabras clave: Mastocitos; POEA; Roundup®; toxicidad; patología toxicológica de peces; inmunohistoquímica; telencéfalo.

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Detalles del artículo

Biografía del autor/a (VER)

Jeraldyn Argüello-Rangel, Universidad de los Llanos Villavicencio Colombia

MVZ, Unillanos. Villavicencio, Colombia.

Pedro A. Triana-García, Ciencias Agrarias Universidad de los Llanos Colombia

MV, MSc, Estudiante de Doctorado en Ciencias Agrarias Unillanos. 

Pedro R. Eslava-Mocha, Universidad de los Llanos Colombia

PhD., Ciencias Agrarias Unillanos. 

pedro.eslava@unillanos.edu.co

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